Purine, 6-bromo-
6-bromo-1H-purine
CAS: 767-69-1
Molecular Formula: C5H3BrN4
Purine, 6-bromo- - Names and Identifiers
| Name | 6-bromo-1H-purine |
| Synonyms | Bb-127e BB-127E NSC 45150 6-Bromopurine 6-BROMOPURINE 6-bromo-purin Purine, 6-bromo- Einecs 212-187-8 6-bromo-1H-purine 6-bromo-7H-purine 6-Bromo-9H-purine 6-bromo-5H-purine 1H-Purine, 6-bromo- (9ci) 1H-Purine, 6-bromo- (9CI) |
| CAS | 767-69-1 |
| EINECS | 212-187-8 |
| InChI | InChI=1/C5H3BrN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10) |
Purine, 6-bromo- - Physico-chemical Properties
| Molecular Formula | C5H3BrN4 |
| Molar Mass | 199.01 |
| Density | 2.28±0.1 g/cm3(Predicted) |
| Melting Point | >300 °C (lit.) |
| Boling Point | 240.9±50.0 °C(Predicted) |
| Flash Point | 239.7°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 1.19E-08mmHg at 25°C |
| Appearance | Solid |
| Color | Pale Beige |
| pKa | 7.39±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.767 |
| MDL | MFCD00022648 |
Purine, 6-bromo- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | UO7513000 |
| HS Code | 29339900 |
Purine, 6-bromo- - Introduction
6-bromo-1H-purine is an organic compound with the chemical formula C5H4BrN5, and its structure contains a bromine atom and a purine ring. The following is a description of the nature, use, preparation and safety information of 6-bromo-1H-purine:
Nature:
-Appearance: 6-bromo-1H-purine is a colorless crystal or white crystalline powder.
-Melting point: about 300-305 degrees Celsius.
-Solubility: 6-bromo-1H-purine has low solubility in water, but it is soluble in acids, alkalis and organic solvents.
Use:
-Chemical synthesis: 6-bromo-1H-purine can be used in organic synthesis reactions, such as amination, substitution reactions, etc.
-Drug research: As an important intermediate, 6-bromo-1H-purine is often used to synthesize drugs or drug candidate compounds.
-Biochemical research: 6-bromo-1H-purine can be used as a labeling reagent for DNA and RNA to help study the structure and function of DNA and RNA.
Preparation Method:
6-bromo-1H-purine can be prepared by the following methods:
-Substitution reaction: 6-bromo-1H-purine is obtained by reacting amino or chloro purine with bromine under alkaline conditions.
-lithium bromination reaction: purine is reacted with lithium bromide in an organic solvent to obtain 6-bromo-1H-purine.
Safety Information:
- 6-bromo-1H-purine has low toxicity, but it is still necessary to pay attention to safe operation. Avoid inhalation and skin contact. Personal protective equipment, such as gloves, safety glasses and protective masks, should be worn during operation.
-In case of contact with skin or eyes, rinse immediately with plenty of water for at least 15 minutes and seek medical help.
- 6-bromo-1H-purine should be stored in a cool, dry place, and away from fire and flammable materials. Chemical waste must be properly managed and disposed of to protect the environment.
Nature:
-Appearance: 6-bromo-1H-purine is a colorless crystal or white crystalline powder.
-Melting point: about 300-305 degrees Celsius.
-Solubility: 6-bromo-1H-purine has low solubility in water, but it is soluble in acids, alkalis and organic solvents.
Use:
-Chemical synthesis: 6-bromo-1H-purine can be used in organic synthesis reactions, such as amination, substitution reactions, etc.
-Drug research: As an important intermediate, 6-bromo-1H-purine is often used to synthesize drugs or drug candidate compounds.
-Biochemical research: 6-bromo-1H-purine can be used as a labeling reagent for DNA and RNA to help study the structure and function of DNA and RNA.
Preparation Method:
6-bromo-1H-purine can be prepared by the following methods:
-Substitution reaction: 6-bromo-1H-purine is obtained by reacting amino or chloro purine with bromine under alkaline conditions.
-lithium bromination reaction: purine is reacted with lithium bromide in an organic solvent to obtain 6-bromo-1H-purine.
Safety Information:
- 6-bromo-1H-purine has low toxicity, but it is still necessary to pay attention to safe operation. Avoid inhalation and skin contact. Personal protective equipment, such as gloves, safety glasses and protective masks, should be worn during operation.
-In case of contact with skin or eyes, rinse immediately with plenty of water for at least 15 minutes and seek medical help.
- 6-bromo-1H-purine should be stored in a cool, dry place, and away from fire and flammable materials. Chemical waste must be properly managed and disposed of to protect the environment.
Last Update：2024-04-09 15:17:59
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Spot supply
Product Name: 6-Bromopurine Visit Supplier Webpage Request for quotationCAS: 767-69-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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